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Home » Blog » 10 Best Altcoin For Cross-Chain DApps In 2025 | Top Interoperable Crypto
CRYPTO

10 Best Altcoin For Cross-Chain DApps In 2025 | Top Interoperable Crypto

Gixona
Last updated: 10/04/2025 10:47 AM
Gixona
6 months ago
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10 Best Altcoin For Cross-Chain DApps In 2025 | Top Interoperable Crypto
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In this article, I will Talk About the best altcoins regarding cross-chain DApps and will center my attention on those that allow interactions between multiple blockchains. With the influx of interest in decentralized applications, cross-chain compatibility becomes absolutely necessary.

Contents
  • Key Points & Best Altcoin For Cross-Chain DApps List
  • 10 Best Altcoin For Cross-Chain DApps In 2025
    • 1.Chainlink (LINK)
    • 2.Polkadot (DOT)
    • 3.Cosmos (ATOM)
    • 4.Avalanche (AVAX)
    • 5.Stargate Finance (STG)
    • 6.Polygon (MATIC)
    • 7.Near Protocol (NEAR)
    • 8.Synthetix (SNX)
    • 9.Thorchain (RUNE)
    • 10.Aave (AAVE)
  • Conclusion

These altcoins are meant to provide interoperability, scalability and safe asset transfers which play an important role in the construction of advanced and effective powerful multichain DApps.

Key Points & Best Altcoin For Cross-Chain DApps List

AltcoinKey Point
Chainlink (LINK)Enables cross-chain data and smart contract connectivity via CCIP.
Polkadot (DOT)Built for interoperability with parachains connecting multiple blockchains.
Cosmos (ATOM)Uses IBC (Inter-Blockchain Communication) for seamless cross-chain transfers.
Avalanche (AVAX)Supports customizable subnets and high-speed cross-chain transactions.
Stargate Finance (STG)Facilitates native asset bridging across chains with unified liquidity.
Polygon (MATIC)Offers cross-chain scaling with zk-rollups and bridges to Ethereum.
Near Protocol (NEAR)Focuses on scalability and bridges to Ethereum via Rainbow Bridge.
Synthetix (SNX)Enables cross-chain synthetic assets trading using liquidity pools.
Thorchain (RUNE)Decentralized liquidity network enabling native asset swaps across chains.
Aave (AAVE)Expanding to cross-chain lending with Aave Portals and layer-2 solutions.

10 Best Altcoin For Cross-Chain DApps In 2025

1.Chainlink (LINK)

Through its Cross-Chain Interoperability Protocol (CCIP), Chainlink (LINK) is known as the best altcoin for DApps in the world of cross-chain technology. CCIP facilitates the safe transfer of data, messaging, and tokens across different blockchains.

Chainlink supports the most important chains which include Ethereum, BNB Chain, Polygon, Avalanche, Arbitrum, Optimism, among others. Its oracle system is used by leading DeFi services, bridging real-world information with smart contracts.

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Chainlink (LINK)

Due to its wide usage, extensive developer’s tools, and security, Chainlink has positioned itself as the industry standard for supporting the development of robust and scalable cross-chain DApps in a perpetually growing network of blockchains that are interoperable.

AspectDetails
NameChainlink (LINK)
PurposeDecentralized Oracle Network
Cross-Chain FeatureChainlink CCIP (Cross-Chain Interoperability Protocol)
Key UseSecure data and token transfer across blockchains
Supported ChainsEthereum, BNB Chain, Polygon, Avalanche, Arbitrum, Optimism, Solana, etc.
Token UtilityLINK used for paying node operators and securing network services
AdoptionUsed by top DeFi, NFT, and enterprise projects for real-world data feeds
Developer BenefitsEVM compatibility, robust APIs, and wide cross-chain integration
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2.Polkadot (DOT)

Polkadot (DOT) is a leading altocoin that was created with a specific purpose of allowing different blockchains to work flawlessly through cross-chain interoperability due to its special relay chain and parachain architecture.

It allows different blockchains to communicate, exchange data, and transfer assets in a secure manner. Different custom blockchains called parachains can be created by developers which get linked to Polkadot’s main network ensuring scalability and interoperability.

Polkadot (DOT)

Polkadot allows connection with other Ethereum, Binance Smart Chain, Kusama and several other Layer-1 chains through bridges.

It has on-chain governance, low fees, shared security through consensus and enables multi-chain DApps to be developed by cross-chain DApp developers which require true multi-chain functionality and performance known as next-generation cross-chain DApps with unparalleled efficiency.

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AspectDetails
NamePolkadot (DOT)
PurposeCross-chain interoperability and scalable multichain network
Cross-Chain FeatureRelay Chain & Parachains architecture
Key UseConnects multiple blockchains to share data and assets securely
Supported ChainsEthereum, BNB Chain, Kusama, and custom parachains via bridges
Token UtilityDOT used for staking, governance, and bonding parachains
AdoptionCore infrastructure for many interoperable Layer-1 projects and DApps
Developer BenefitsSubstrate SDK for custom chain development and seamless ecosystem integration
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3.Cosmos (ATOM)

Cosmos (ATOM) is a top altcoin for cross-chain DApps, built around its Inter-Blockchain Communication (IBC) protocol.

This protocol enables seamless communication and asset transfers between independent blockchains within the Cosmos ecosystem.

Chains like Osmosis, Cronos, Secret Network, Terra, and Kava are all IBC-compatible, allowing DApps to operate across multiple networks without relying on centralized bridges.

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Cosmos (ATOM)

Cosmos offers modular SDK tools for developers to build scalable, customizable blockchains that can easily interoperate.

With fast finality, low fees, and a growing ecosystem of interconnected blockchains, Cosmos is a powerful foundation for building efficient cross-chain decentralized applications.

AspectDetails
NameCosmos (ATOM)
PurposeInteroperability between independent blockchains
Cross-Chain FeatureIBC (Inter-Blockchain Communication Protocol)
Key UseEnables secure data and asset transfer across sovereign blockchains
Supported ChainsOsmosis, Secret Network, Terra, Cronos, Kava, Akash, and more via IBC
Token UtilityATOM used for staking, governance, and network security
AdoptionPowers a growing ecosystem of IBC-enabled chains and DeFi platforms
Developer BenefitsCosmos SDK for easy blockchain creation and cross-chain functionality

4.Avalanche (AVAX)

Avalanche (AVAX) is particularly suited for developing cross-chain DApps due to its high-performance capabilities. It also offers fast, low-cost transactions and a unique architecture with three chains (X-Chain, C-Chain, and P-Chain).

Avalanche has proprietary bridges such as the Avalanche Bridge (AB) to Ethereum and is expanding support to other blockchains like BNB Chain, Bitcoin, and Polygon. Developers are able to deploy custom subnets aligned with DApp requirements which allows for greater compliance and scalability.

Avalanche (AVAX)

Avalanche’s capabilities in EVM, strong developer resources, and growing support from multichains make it easy, secure, and flexible for the development of cross-chain decentralized applications.

AspectDetails
NameAvalanche (AVAX)
PurposeHigh-speed, scalable platform for decentralized applications
Cross-Chain FeatureNative support for cross-chain communication via X-Chain, C-Chain, and P-Chain
Key UseAsset transfers, smart contracts, and subnet-powered DApps
Supported ChainsEthereum (via Avalanche Bridge), BNB Chain, Bitcoin, Polygon (via bridges)
Token UtilityAVAX used for staking, fees, and securing the network
AdoptionUsed by DeFi, GameFi, and enterprise apps for scalable multichain solutions
Developer BenefitsEVM-compatible, custom subnets, fast finality, and low transaction fees

5.Stargate Finance (STG)

Stargate Finance (STG) is a cross-chain liquidity protocol that allows the transfer of native assets across different blockchains. With LayerZero, Stargate allows for composability between chains with true interoperability without having to wrap tokens.

Major chains like Ethereum, BNB Chain, Avalanche, Arbitrum, Optimism, Polygon, and Fantom are supported. Developers can create DApps that can utilize assets from different networks instantly and seamlessly.

Stargate Finance (STG)

Stargate eliminates the need for traditional bridges with instant guaranteed finality and unified liquidity pools. STG is used for governance and staking which helps in maintaining the network’s operations. For building scalable and secure cross-chain DApps, Stargate serves as a cardinal infrastructure component.

AspectDetails
NameStargate Finance (STG)
PurposeCross-chain liquidity and native asset bridging
Cross-Chain FeatureBuilt on LayerZero; supports direct, composable asset transfers
Key UseEnables native token swaps across chains without wrapping
Supported ChainsEthereum, BNB Chain, Avalanche, Polygon, Arbitrum, Optimism, Fantom
Token UtilitySTG used for governance and staking
AdoptionIntegrated with DeFi protocols for unified cross-chain liquidity
Developer BenefitsInstant finality, no need for synthetic assets or centralized bridges

6.Polygon (MATIC)

Polygon (MATIC) Recent news on the Polygon ecosystem has positioned it as the number one layer 2 solution and the go-to platform for building cross-chain capable DApps.

It encompasses many technologies like POS Chain, zkEVM, and Polygon CDK for seamless scalability and interoperability, as well as supporting multiple chains. Its native and third party bridges enable bridging assets to and from Ethereum, BNB Chain, Avalanche, Arbitrum, Optimism, etc.

Polygon (MATIC)

Developers are well served with EVM compatibility, low fees, and fast finality. Expanding ecosystem with DeFi, gaming, and enterprise DApps makes Polygon an all-in-one multichain development hub. Strong infrastructure and active development to a growing list of project makes it appealing for efficient cross-chain applications.

AspectDetails
NamePolygon (MATIC)
PurposeScalable, EVM-compatible platform for multichain DApps
Cross-Chain FeatureNative bridges and zk-rollups for asset and data transfers
Key UseCross-chain DeFi, NFTs, and enterprise DApp deployment
Supported ChainsEthereum, BNB Chain, Avalanche, Arbitrum, Optimism, and more via bridges
Token UtilityMATIC used for gas fees, staking, and governance
AdoptionWidely used in DeFi, gaming, and Web3 ecosystems
Developer BenefitsEVM compatibility, low fees, fast finality, zkEVM support

7.Near Protocol (NEAR)

NEAR Protocol (NEAR) implements a highly scalable Layer-1 blockchain focused on end-user and developer-friendly cross-chain DApp ecosystem. It is best known for the Rainbow Bridge, which allows direct interoperability with Ethereum.

NEAR also works with Aurora (an EVM-compatible environment) and allows bridging through third-party solutions to the BNB Chain, Polygon, and other networks. Near’s sharded architecture provides low fees and high throughput with fast finality.

Near Protocol (NEAR)

Developers are able to create sophisticated multichain applications easily using Rust or AssemblyScript. NEAR provides a multi-chain environment with extensive focus scalability, UX and interconnectivity, making it one of the most advanced platforms for cross-chain decentralized application development.

AspectDetails
NameNear Protocol (NEAR)
PurposeScalable Layer-1 platform for user-friendly, cross-chain DApps
Cross-Chain FeatureRainbow Bridge for interoperability with Ethereum and more
Key UseEnables seamless asset and contract interaction across chains
Supported ChainsEthereum, Aurora (EVM), BNB Chain, Polygon (via third-party bridges)
Token UtilityNEAR used for transaction fees, staking, and governance
AdoptionGrowing ecosystem in DeFi, gaming, and creator economies
Developer BenefitsSharded architecture, low fees, fast finality, and multiple language support

8.Synthetix (SNX)

Synthetix (SNX) is a protocol that is both decentralized and capable of cross-chain trading of synthetic assets. Its primary support lies within Ethereum and Optimism, but Synthetix also supports other synethic assets like sUSD and sETH.

Synthetix increases the accessibility of liquidity through other chains such as Base and Arbitrum which are integrated through LayerZero and other bridges.

Synthetix (SNX)

Using its modular design, Synthetix is able to integrate other protocols like Kwenta and Lyra for cross-chain applications.

Currently, SNX can be used for staking, governance and collateral backing. Synthetix provides the infrastructure for cross-chain synthetic DeFi derivatives trades while enabling widespread adoption.

AspectDetails
NameSynthetix (SNX)
PurposeDecentralized protocol for synthetic asset creation and trading
Cross-Chain FeatureCross-chain liquidity via LayerZero and deployment on multiple Layer-2s
Key UseEnables trading of synthetic assets across supported blockchains
Supported ChainsEthereum, Optimism, Base, Arbitrum (via cross-chain integrations)
Token UtilitySNX used for staking, collateral, and governance
AdoptionIntegrated with platforms like Kwenta and Lyra for DeFi derivatives trading
Developer BenefitsComposable smart contracts, cross-chain liquidity access, and modular design

9.Thorchain (RUNE)

Thorchain (RUNE) is a cross-chain swap protocol that provides cross-chain swaps natively without wrapped assets or intermediary central bridges.

It currently supports Bitcoin, Ethereum, BNB Chain, Litecoin, Bitcoin Cash, Dogecoin, Avalanche, with more integrations planned.

Thorchain (RUNE)

Users and DApps can swap assets across chains while retaining custody of their native tokens, or namesake currencies. It is built Cosmos SDK and Tendermint consensus, and RUNE is the primary asset used for settling pools and securing the system.

Thorchain is one of the most preferred platforms for developing truly permissionless, trustless, and decentralized cross-chain DApps due to it’s architectural design.

AspectDetails
NameThorchain (RUNE)
PurposeDecentralized cross-chain liquidity and native asset swaps
Cross-Chain FeatureDirect swaps without wrapped tokens or centralized bridges
Key UseEnables native token trading across multiple Layer-1 blockchains
Supported ChainsBitcoin, Ethereum, BNB Chain, Litecoin, Bitcoin Cash, Dogecoin, Avalanche
Token UtilityRUNE used for liquidity, security bonding, and network fees
AdoptionUsed by DEXs and DeFi tools for true cross-chain trading
Developer BenefitsNative asset support, high security, and cross-chain composability
Visit Now

10.Aave (AAVE)

Aave (AAVE) is one of the first decentralized lending protocols which is now venturing into cross-chain capabilities through Aave Portals. These allow for liquidity to be moved across supported chains without needing to bridge tokens.

Aave is deployed on Ethereum, Polygon, Avalanche, Optimism, Arbitrum, Base, and Fantom, therefore it has a broad multichain DeFi marketplace. Using Aave Portals, LayerZero, and other integrations, the protocol seeks to provide seamless lending, borrowing, and asset transfer functionalities across chains.

Aave (AAVE)

The AAVE token is used for governance and staking in the Safety Module. AAVE is backed by Aave’s cross-chain lending approach which makes Aave a pillar in the construction of scalable interoperable DeFi solutions.

AspectDetails
NameAave (AAVE)
PurposeDecentralized lending and borrowing protocol
Cross-Chain FeatureAave Portals for cross-chain liquidity movement
Key UseEnables lending and borrowing across multiple blockchain networks
Supported ChainsEthereum, Polygon, Avalanche, Optimism, Arbitrum, Base, Fantom
Token UtilityAAVE used for governance and staking in the Safety Module
AdoptionWidely integrated in DeFi, with billions in total value locked
Developer BenefitsCross-chain liquidity tools, robust APIs, and multi-network deployment

Conclusion

In Conclusion The most effective altcoins for cross-chain DApps like Chainlink, Polkadot, Cosmos, Avalanche, and others offer utmost interoperability, scalability, and developer hardware.

Each one facilitates transfer of assets and data across several networks, which enhances the security and efficiency of decentralized applications.

These projects are leaders in multichain development, and are changing the face of Web3 with cross-chain composability and connectivity.

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