Grayscale Investments has released its updated Top 20 crypto token list for Q3 2025, showcasing notable changes that reflect shifting market dynamics and institutional sentiment. The updated selection introduces Avalanche (AVAX) and Morpho (MORPHO), while continuing to exclude long-established names like XRP and Cardano (ADA).
Both investors and analysts closely monitor this list, and it shows which digital assets Grayscale considers most promising based on market data, performance metrics, and technological progress. The recent update in the firm indicates the increasing trend of focusing more on innovation and current drive rather than on the established brand.
AVAX and Morpho Climb as Lido and Optimism Drop
Avalanche and Morpho received their spot on the Q3 list since these two projects have shown a remarkable performance and expansion in utility over the past quarters. The growth of Morpho occurred after the launch of the V2 protocol, which was to connect decentralized finance (DeFi) and conventional institutions. Grayscale observed that because of its on-chain efficiency as well as market traction, lending activity conducted by Morpho has drawn the interest of institutional players.

In the meantime, Lido DAO (LDO) and Optimism (OP) removed their existence from rankings. Much like both are central to the Ethereum ecosystem, Grayscale stated that the regulatory pressure growing around staking services poses a threat to Lido’s revenue model. In the case of optimism, its token could not retain economic value despite its high levels of technological adoption, making it out of the top-tier list.
These shuffles mark an overall shift in the valuation by Grayscale that will shift toward more actively functioning in the market, liquid, and project fundamentals, rather than long-term entrenchment in popular networks.
XRP and Cardano Snubbed Again Despite Market Momentum
Once again, in one more quarter, Grayscale does not include two of the most common and actively traded and discussed cryptocurrencies, XRP and Cardano, in its Top 20. Their non-existence stands out, particularly in the industry discussions on possible spot XRP ETFs that keep gaining traction.
Recently, Bloomberg analysts boosted the chances of getting the XRP ETF passed, which added to the level of interest in how it will contribute to institutional portfolios. Nevertheless, Grayscale made a decision to leave the two of these assets out, which brought a controversial discussion with the cryptocurrency community about the decision to select Grayscale.
This non-inclusion of XRP and ADA can lead to the fact that the decision-making process Grayscale adopts with respect to network use, as well as developer activity and regulatory clarity, is also questioned. The two tokens are actively traded and scalable with market caps, but are yet to enjoy the spotlight of Grayscale priority watchlist.
Grayscale Expands Focus With AI Sector Index
Alongside the token reshuffle, Grayscale has completed its launch of the AI Crypto Sector index, which now includes 24 tokens representing a combined market cap of $15 billion. Bittensor (TAO) at the top of the index shows the field of artificial intelligence and decentralized infrastructure as one of the rising areas of interest.
The most recent sector report of Grayscale also indicates emerging market trends in the Q2 of 2025. Bitcoin retained its leadership in the Currencies category, and Smart Contract Platforms experienced a rise in active users and a drop in their fee revenue, with memecoins losing ground. The other areas of interest involve the increase and adoption of next-gen innovative contract protocols as well as DeFi lending.
Institutional investors often cite the Grayscale Top 20 and sector indices when determining the trends in the market. With the industry changing, these lists end up informing sentiment and perhaps also forcing capital into digital assets.
Conclusion
Grayscale’s Q3 update introduces fresh names like Avalanche and Morpho while excluding XRP and Cardano once again. With the firm also launching a dedicated AI token index, its latest move highlights changing market priorities and provides insights into where institutional interest may be headed next.
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